Biochemistry and Molecular Biology

University of Texas Medical Branch


Current Students - Courses

BMB Core Course Offerings

BMB 6195 Seminar- 1 Credit Hour
Syllabus

Students must register for the Seminar course (BMB 6195) in years 2, 3 and 4 (three consecutive years after they enter into the BMB graduate program).  Each student will attend student seminars regularly and, in addition, each student will present one seminar per year in their third and fourth years.
Prerequisite: BBSC Core
Instructor: Sastry, Choi
Term offered: II
Year offered: Annually
Hours per week: Seminar 1

BMB 6111 Current Concepts in Biochemistry & Molecular Biology (Faculty Seminar) - 1 Credit Hour
Syllabus

BMB-committed first year BBSC students and BMB students must register for BMB 6196 every fall and spring term through their fourth year.  Students will attend faculty seminars offered by the department of Biochemistry & Molecular Biology, KECK Center, or Sealy Center for Structural Biology & Molecular Biophysics.
Prerequisite: BBSC Core
Instructor: Toliver-Kinsky, Sastry, Oberhauser
Term offered: I & II
Year offered: Annually
Hours per week: 1 hour per seminar attended

BMB  6207 Cell and Gene Regulation in Stress Biology - 2 Credit Hours
Syllabus

This course considers the molecular and cellular regulatory biology of stress.  A particular focus will be the role of posttranslational modification of proteins, structural consequences of these modifications and the functional outcomes of stress with particular focus on cell death processes and inflammation.
Prerequisite: Consent of Instructor or BBSC Core
Instructor: Perez-Polo
Term offered: I
Year offered: Annually
Hours per week:  2, 10 Week Course

BMB  6208 Genomics, Proteomics and Bioinformatics – 2 Credit Hours
Syllabus

Lecturers will select seminal recent papers on principles and novel techniques used in the interpretation of DNA micro arrays, protein arrays and data mining of structural and functional databases.  Each student is requested to read all papers, and present one paper with additional background information in a 45-minute lecture. The faculty will provide additional advice on the context of this paper in the literature, might complement the student presentation with comments from his expertise on particular techniques, and will stimulate the discussion on the content of paper.
Prerequisite: Consent of instructor or BBSC core
Instructor: Braun
Term offered: I
Year offered: Annually
Hours per week: 2, 10 Week Course

BMB  6209 DNA Repair, Mutagenesis, Replication, and Environmental Toxicology - 2 Credit Hours
Syllabus

This course, which is in the tutorial format, deals with various aspects of DNA repair and replication, mutagenesis, and environmental toxicology. A particular focus point will be the interrelationships among repair processes and other important cellular functions.
Prerequisite: Consent of instructor or BBSC core
Instructor: L. Prakash,
Term offered: I
Year offered: Annually
Hours per week:  2, 10 Week Course

BMB  6222 Hormone Action and Cancer Cell Biology – 2 Credit Hours
Syllabus

This course provides students a clear understanding of the issues current in several major areas of hormone action, especially as related to cancer cell biology.  These areas include action of nuclear hormone receptors, G-protein associated receptors and the hormones that act through them, non-G-protein associated membrane receptors and the hormones that act through them, and signaling molecules that act by way of hormone-like systems, but not usually classified strictly as hormones.  In the course of examining these major systems, we will include consideration of aspects of signaling pathways as well as ligand: receptor actions.
Prerequisite: Consent of instructor or BBSC core
Instructor:  TBD
Term offered: I
Year offered: Annually
Hours per week:  2, 10 Week Course

BMB 6223 Molecular, Cellular and Genetic Basis of Aging

This course encompasses the principles and novel techniques used in understanding the molecular, cellular (physiological) and genetic factors that regulates the rate of aging and longevity.  The mechanisms of aging will be clarified by integrating genetic data with molecular, cellular and physiological outcomes and environmental factors.  The course discusses how organisms develop the molecular and biochemical characteristics of aging.  A major consideration is how environmental factors interact with genetic factors to influence a aging processes.
Prerequisite: Consent of instructor or BBSC core
Instructor: John Papaconstantinou
Term offered: II
Year offered: Bi-Annually
Hours per week:  2, 10 Week Course

BMB 6224 Structural Biology and Biophysical Chemistry – 2 Credit Hours
Syllabus

This course deals with the role of biophysical methods, including structural biology, solution biophysical and computational approaches, in the study of proteins in the proteomic era.  The focus is on conformational changes and macromolecular assembly, the utility of dynamic and static structural data, and the necessity to combine experimental approaches to obtain a full functional description.
Prerequisite: Consent of instructor or BBSC core
Consent of instructor or BBSC core
Instructor:  James Lee
Term offered: II
Year offered: Annually
Hours per week:  2, 10 Week Course